I hadn’t found this before, but from any application you can hookup a SessionSwitchEventHandler. Obviously your application will need to be running, but so long as it is:
Microsoft.Win32.SystemEvents.SessionSwitch += new Microsoft.Win32.SessionSwitchEventHandler(SystemEvents_SessionSwitch);
void SystemEvents_SessionSwitch(object sender, Microsoft.Win32.SessionSwitchEventArgs e)
{
if (e.Reason == SessionSwitchReason.SessionLock)
{
//I left my desk
}
else if (e.Reason == SessionSwitchReason.SessionUnlock)
{
//I returned to my desk
}
}