It looks like you could use numpy.bincount here:
import numpy as np
def radial_profile(data, center):
y, x = np.indices((data.shape))
r = np.sqrt((x - center[0])**2 + (y - center[1])**2)
r = r.astype(np.int)
tbin = np.bincount(r.ravel(), data.ravel())
nr = np.bincount(r.ravel())
radialprofile = tbin / nr
return radialprofile