You can use Drupal and Django side-by-side on the same server for different portions of your web site, but they will be entirely separate systems. They cannot interact in any meaningful fashion (except possibly a Django app making web API calls to Drupal, if Drupal has a web API).
Django is a Python-based web development framework. Drupal is a CMS (and framework, through its module system) written in PHP. They really can’t use each other.