Put the data into a Buffer using the ‘base64’ encoding, then write this to a file:
var fs = require('fs');
var string = "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAUAAAAFCAYAAACNbyblAAAAHElEQVQI12P4//8/w38GIAXDIBKE0DHxgljNBAAO9TXL0Y4OHwAAAABJRU5ErkJggg==";
var regex = /^data:.+\/(.+);base64,(.*)$/;
var matches = string.match(regex);
var ext = matches[1];
var data = matches[2];
var buffer = Buffer.from(data, 'base64');
fs.writeFileSync('data.' + ext, buffer);